3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine synthesis
- Product Name:3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- CAS Number:329214-79-1
- Molecular formula:C11H16BNO2
- Molecular Weight:205.06
626-55-1
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73183-34-3
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329214-79-1
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Yield:329214-79-1 95%
Reaction Conditions:
with PdCl2(dppf);potassium acetate in toluene at 100; for 3 h;
Steps:
I.2.3; I.5.3; I.6.4; III.12.3 Core side 1-I-2 Synthesis
3-Bromopyridine (130 g, 822.8 mmol)(250.73 g, 987.3 mmol) and 4,4,4 ', 4', 5,5,5 ', 5'-octamethyl-2,2'-bi (1,3,2-dioxaborolane) and PdCl2 (20.16 g, 24.7 mmol)And potassium acetate (242.24 g, 2,468.4 mmol) was added to a round bottom flask,Toluene (4,000 mL)And the mixture was stirred at 100 ° C for 3 hours.When the reaction is terminated, the reaction product is quenched by adding water, and water in the reaction product is removed. After filtration under reduced pressure,The organic layer was dried over MgSO4 and concentrated to give 160.28 g (yield: 95%) of the product.
References:
Duksan Neolux Co.,Ltd.;Yoon Jin-ho;Jeong Ho-yeong;Park Mu-jin;Kim Jeong-seok;Lee Seon-hui KR2018/128292, 2018, A Location in patent:Page/Page column 22; 23; 25; 26; 40
626-60-8
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73183-34-3
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329214-79-1
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76-09-5
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160688-99-3
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329214-79-1
240 suppliers
$6.00/1g
626-55-1
539 suppliers
$5.00/5 / G
76-09-5
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$8.19/250mg
121-43-7
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329214-79-1
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59-67-6
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73183-34-3
556 suppliers
$6.00/5g
329214-79-1
240 suppliers
$6.00/1g