4-BROMO-3'-METHOXYBIPHENYL synthesis

7synthesis methods

Product Name:4-BROMO-3'-METHOXYBIPHENYL
CAS Number:74447-69-1
Molecular formula:C13H11BrO
Molecular Weight:263.13

106-37-6 Synthesis

106-37-6
472 suppliers
$9.00/5g

10365-98-7 Synthesis

10365-98-7
406 suppliers
$9.00/10g

74447-69-1
27 suppliers
$419.00/1g

Yield:74447-69-1 95%

Reaction Conditions:

with sodium carbonate in ethanol;water at 80; for 0.25 h;Catalytic behavior;Suzuki-Miyaura Coupling;

Steps:

2.4. Typical procedure for the Suzuki-Miyaura cross coupling reaction

General procedure: Aryl halide (1 mmol), phenylboronic acid (1 mmol), Na2CO3(2 mmol) and Fe2O3(at)FLGPd⁰ nanocatalyst (0.0004 g) were added to a round-bottomed flask containing 3mL of aqueous 50% ethanol(v/v%), and the mixture was stirred at 80 °C for the time listed in Table 2. The progress was monitored by TLC ((n-hexane or n-hexane/EtOAc, 9: 1) or GC. After completion of the reaction, the reaction mixture was cooled to room temperature and the catalyst was separated by an external magnet. Then, the reaction mixture was diluted with water and the resultant mixture extracted with n-hexane to isolate the biphenyl products. The combined organic layers were dried over MgSO4, and the solvent was evaporated under reduced pressure.

References:

Rafiee, Fatemeh;Khavari, Parvaneh;Payami, Zahra;Ansari, Narges [Journal of Organometallic Chemistry,2019,vol. 883,p. 78 - 85]