4-Chloro-7-nitrobenzofurazan synthesis
- Product Name:4-Chloro-7-nitrobenzofurazan
- CAS Number:10199-89-0
- Molecular formula:C6H2ClN3O3
- Molecular Weight:199.55
7116-16-7
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$36.00/1g
10199-89-0
198 suppliers
$15.00/250mg
Yield:10199-89-0 54%
Reaction Conditions:
with sodium nitrate;sulfuric acid at 0 - 85; for 0.583333 h;
Steps:
2.1.7. 4-Chloro-7-nitrobenzo[c][1,2,5]oxadiazole (3) [4]
2.1.7. 4-Chloro-7-nitrobenzo[c][1,2,5]oxadiazole (3) [4] A solution of NaNO3 (14.6 g, 172 mmol) in H2SO4 (250 g, 2.55 mol) was cooled to 0 °Cbefore 4-chlorbenzo[c][1,2,5]oxadiazole (4.59 g, 29.6 mmol) was added to the solution. Afterstirring for 5 min at 0 °C the reaction mixture was heated to 85 °C for 30 min. Thereafter icewater (250 mL) was added and cooled to 0 °C. The precipitate was filtered off andrecrystallized from an ethanol water mixture (1.6:1, 400 mL) to give 4-chloro-7-nitrobenzo[c][1,2,5]oxadiazole (3, 3.22 g, 16.1 mmol, 54%) as yellow needles.
References:
Börgardts, Markus;Müller, Thomas J. J. [Beilstein Journal of Organic Chemistry,2017,vol. 13,p. 768 - 778] Location in patent:supporting information
1194-66-7
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$65.00/50mg
10199-89-0
198 suppliers
$15.00/250mg
608-31-1
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$12.00/25g
10199-89-0
198 suppliers
$15.00/250mg
601-88-7
162 suppliers
$8.00/5g
10199-89-0
198 suppliers
$15.00/250mg