ChemicalBook CAS DataBase List 5-Aminouracil

5-Aminouracil synthesis

6synthesis methods

Product Name:5-Aminouracil
CAS Number:932-52-5
Molecular formula:C4H5N3O2
Molecular Weight:127.1

611-08-5 Synthesis

611-08-5
382 suppliers
$5.00/5g

932-52-5
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$33.92/5g

Yield:932-52-5 92%

Reaction Conditions:

with Sodium hydrogenocarbonate;Na₂S₂O₃ in lithium hydroxide monohydrate at 75; for 4 h;Reagent/catalyst;Temperature;

Steps:

11.1; 12.1; 13.1 step 1:

50 g of Na 2S 2 O 4 were added in portions to a saturated aqueous solution of 10 g of 5-nitrouracil and 20 g of sodium bicarbonate and stirred at 75° C. for 4 hours. The resulting white precipitate was filtered, washed with water and dried to obtain 7.4 g of 5-aminouracil (yield: 92%).

References:

WO2022/96015,2022,A1 Location in patent:Page/Page column 24-26

51-20-7 Synthesis