ChemicalBook CAS DataBase List (R)-(R)-1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate(WXC03446)

(R)-(R)-1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate(WXC03446) synthesis

2synthesis methods

Product Name:(R)-(R)-1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate(WXC03446)
CAS Number:616866-21-8
Molecular formula:C18H25NO3
Molecular Weight:303.4

894795-19-8
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(R)-(R)-1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate(WXC03446)

616866-21-8
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Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: lithium hexamethyldisilazane / hexane; tetrahydrofuran / 1 h / -78 °C
1.2: 16 h / -78 - 20 °C
2.1: potassium hydroxide; water / methanol / 4 h / 65 °C
3.1: 1,1'-carbonyldiimidazole / toluene

References:

WO2018/26869,2018,A1

(R)-3-hydroxy-1-methyl-2,5-pyrrolidinedione

131237-81-5
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616866-21-8
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References

(R)-(R)-1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate(WXC03446) Related Search:

alpha-Cyclopentylmandelic acid Methyl (R)-(-)-cyclopentylmandelate CYCLOPENTYL PHENYL KETONE (S)-1-methylpyrrolidin-3-yl (R)-2-cyclopentyl-2-hydroxy-2-phenylacetate Benzaldehyde 5-Nitroisophthalic acid Methyl benzoylformate Benzoylformic acid CYCLOPENTYL BENZOATE