ChemicalBook CAS DataBase List Benzenesulfonamide

Benzenesulfonamide synthesis

13synthesis methods

Product Name:Benzenesulfonamide
CAS Number:98-10-2
Molecular formula:C6H7NO2S
Molecular Weight:157.19

Benzenesulfonamide is obtained by amination of benzenesulfonyl chloride.

98-09-9
341 suppliers
$12.00/25g

98-10-2
333 suppliers
$18.00/25g

Yield:98-10-2 96%

Reaction Conditions:

with ammonia in water at -10; for 3 h;

Steps:

A

200 ml of aq. NH₃ is cooled to -1O⁰C and treated with benzenesulfonylchloride (13 g, 73 mmol). The resulting mixture is stirred at this temperature for 3h. When TLC confirmed the completion of the reaction, the reaction mixture is warmed to rt, and the resulting solid is filtered, washed with water and dried under vacuum to afford the title compound (11.1 g, 96 %). LC/MS: (ES+): 158.2, (ES-): 156.2.

References:

WO2007/23186,2007,A1 Location in patent:Page/Page column 40