ChemicalBook CAS DataBase List Cyclohexanone

Cyclohexanone synthesis

15synthesis methods

Product Name:Cyclohexanone
CAS Number:108-94-1
Molecular formula:C6H10O
Molecular Weight:98.14

It may be synthesized on a laboratory scale by the oxidation of cyclohexanol.

95-57-8 Synthesis

95-57-8
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$10.00/5g

108-94-1
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$12.00/50g

Yield:108-94-1 100%

Reaction Conditions:

with sodium formate;sodium hydroxide in water at 120; pH=12;

Steps:

2.4. General procedure for the flow hydrogenation

General procedure: A premixed mixture of phenolic compound (1a-h) and sodium formate (2, 3 equiv.) in H2O (0.1 M) was prepared in a flask with the function of the reservoir, and the mixture was adjusted to pH 12.0 with the addition of 5 M aq NaOH. POLITAG-Pd(0)-L1 (8 wt%, 0.54 mmol,718.3 mg) was dispersed in solid glass beads and glass powder and was charged in a stainless-steel reactor; the equipment was connected byusing the appropriate valves, and a back pressure regulator was placedon the outlet tube. The packed reactor was placed into a thermostated box, and the mixture was pumped through the catalyst columns at120 °C. The conversion of 1a-i and its selectivity were periodically monitored by GLC analysis.

References:

Campana, Filippo;Ferlin, Francesco;Silvetti, Matteo;Trombettoni, Valeria;Vaccaro, Luigi;Valentini, Federica [Molecular catalysis,2021,vol. 509]