Homosalate synthesis
1synthesis methods
- Product Name:Homosalate
- CAS Number:118-56-9
- Molecular formula:C16H22O3
- Molecular Weight:262.34
Yield:118-56-9 81.1%
Reaction Conditions:
with potassium carbonate;ammonium bromide at 180; for 13 h;Concentration;Reagent/catalyst;Temperature;
Steps:
2 Example 2
250 ml three-necked flask, 10.0 g of methyl salicylate, 23.3 g of 3,3,5-trimethylcyclohexanol, 0.50 g of potassium carbonate,Ammonium bromide 0.1g, heated to 180 reaction 13h, gas chromatography detection reaction system methyl salicylate conversion was 97.2%.To vacuum distillation unit, the former fraction recovery to be applied,ColorlessMing of the Hu Moluo13.98 g,Yield 81.1%, GCPurity greater than 99%.
References:
CN105541634,2016,A Location in patent:Paragraph 0023; 0024