O,O-Dimethyl phosphoramidothioate synthesis

Yield:17321-47-0 99.8%

Reaction Conditions:

with ammonia in dichloromethane at 5 - 10; for 10 h;Solvent;Temperature;

Steps:

1-6 Example 1
Put 171g (1.0mol) of O,O-dimethylthiophosphoryl chloride and 34.2g of dichloromethane into a 250ml reaction flask and stir and mix evenly; then pass ammonia into the reaction, and control the reaction temperature at 5-10°C. Reaction for 10 hours under stirring; sampling and analysis of O,O-dimethyl thiophosphoryl chloride mass fractionPut 171g (1.0mol) of O,O-dimethylthiophosphoryl chloride and 34.2g of dichloromethane into a 250ml reaction flask and stir and mix evenly; then pass ammonia into the reaction, and control the reaction temperature at 5-10°C. Reaction for 10 hours under stirring; sampling and analysis of O,O-dimethyl thiophosphoryl chloride mass fraction

References:

CN112300210, 2021, A Location in patent:Paragraph 0016-0027

FullText