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112111-47-4

112111-47-4 Structure

112111-47-4 Structure
IdentificationBack Directory
[Name]

(S)-Modafinil
[CAS]

112111-47-4
[Synonyms]

CRL 40983
(S)-Modafinil
(S)-(+)-Modafinil
ArModafinil IMpurity H
2-[(S)-(Diphenylmethyl)sulfinyl]acetamide
AcetaMide, 2-[(S)- (diphenylMethyl)sulfinyl]-
Acetamide,2-[(S)-(diphenylmethyl)sulfinyl]- (Related Reference)
[Molecular Formula]

C15H15NO2S
[MOL File]

112111-47-4.mol
[Molecular Weight]

273.354
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

157-159°C
[Boiling point ]

559.1±50.0 °C(Predicted)
[density ]

1.283±0.06 g/cm3(Predicted)
[storage temp. ]

-20?C Freezer
[solubility ]

DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.25 mg/ml
[form ]

A crystalline solid
[pka]

14.88±0.40(Predicted)
[CAS DataBase Reference]

112111-47-4
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Used for treatment of excessive sleepiness, a1-adrenoceptor agonist
[Uses]

Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.
[Definition]

ChEBI:(S)-modafinil is a 2-[(diphenylmethyl)sulfinyl]acetamide that has S configuration at the sulfur atom. The racemate comprising (S)-modafinil and its enantiomer, armodafinil, is known as modafinil and is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The enantiomers have similar pharmacological actions in animals. It has a role as a central nervous system stimulant and a eugeroic. It is an enantiomer of an armodafinil.
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