| Identification | Back Directory | [Name]
Pemetrexed-d5 Disodium Salt | [CAS]
1129408-57-6 | [Synonyms]
Pemetrexed-d5 Disodium Salt
N-[4-[2-(2-AMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]-L-glutaMic Acid-d5 SodiuM Salt
Pemetrexed D5 disodium saltQ: What is
Pemetrexed D5 disodium salt Q: What is the CAS Number of
Pemetrexed D5 disodium salt Q: What is the storage condition of
Pemetrexed D5 disodium salt Q: What are the applications of
Pemetrexed D5 disodium salt | [Molecular Formula]
C20H18N5Na2O6 | [MDL Number]
MFCD18385037 | [MOL File]
1129408-57-6.mol | [Molecular Weight]
470.366 |
| Chemical Properties | Back Directory | [Melting point ]
> 220?C (dec.) | [storage temp. ]
-20°C Freezer | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Pale Yellow | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Solid | [Uses]
Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic. | [Definition]
ChEBI: Pemetrexed disodium is an organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). It has a role as an antineoplastic agent, an antimetabolite, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor and an EC 2.1.1.45 (thymidylate synthase) inhibitor. It contains a pemetrexed(2-). |
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