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114915-19-4

114915-19-4 Structure

114915-19-4 Structure
IdentificationBack Directory
[Name]

Docetaxel impurity 1/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-6,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(((2,2,2-trichloroethoxy)carbonyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl
[CAS]

114915-19-4
[Synonyms]

7-TROC-10-DAB
Docetaxel Impurity 26
Docetaxel Impurity 41
Cephalomannine Impurity 4
7-(2,2,2-Trichloroethyloxycarbonyl)-10-deacetylbaccatin III
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-6,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(((2,2,2-trichloroethoxy)carbonyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate
Carbonic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-4-yl 2,2,2-trichloroethyl ester
Docetaxel impurity 1/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-6,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(((2,2,2-trichloroethoxy)carbonyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl
[Molecular Formula]

C32H37Cl3O12
[MOL File]

114915-19-4.mol
[Molecular Weight]

719.99
Chemical PropertiesBack Directory
[Boiling point ]

809.8±65.0 °C(Predicted)
[density ]

1.50±0.1 g/cm3(Predicted)
[pka]

11.35±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

7-(2,2,2-Trichloroethyloxycarbonyl)-10-deacetylbaccatin III is a derivative of Baccatin III (B101000), which is a precursor to Paclitaxel (P132500), a neoplasm inhibitor used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi''s sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
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