ChemicalBook--->CAS DataBase List--->118971-03-2

118971-03-2

118971-03-2 Structure

118971-03-2 Structure
IdentificationBack Directory
[Name]

(S)-2-(Methoxydiphenylmethyl)pyrrolidine
[CAS]

118971-03-2
[Synonyms]

-2-(Methoxydiphenylmethyl)
(S)-2-(Methoxydiphenylmethyl)pyrrolidine
(2S)-2-(Methoxydiphenylmethyl)pyrrolidine
(2S)-2-[Diphenyl(methoxy)methyl]pyrrolidine
Pyrrolidine, 2-(methoxydiphenylmethyl)-, (2S)-
(2S)-2-[Diphenyl(methoxy)methyl]tetrahydropyrrole
(S)-2-(MethoxydiphenylMethyl)pyrrolidine 95% (HPLC)
[Molecular Formula]

C18H21NO
[MDL Number]

MFCD09750440
[MOL File]

118971-03-2.mol
[Molecular Weight]

267.37
Chemical PropertiesBack Directory
[Boiling point ]

368.7±32.0 °C(Predicted)
[density ]

1.070±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

10.09±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P280-P305+P351+P338
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

(S)-2-(Methoxydiphenylmethyl)pyrrolidine is a diphenylprolinol methyl ether, which can be used as a catalyst to synthesize:
  • Enantioselective ketones via intermolecular asymmetric Michael addition of aldehydes to nonactivated enones.
  • Stereoselective chiral bipyrazolidin-3-one derivatives by dipolar cycloaddition reaction of azomethine imines with α, β-unsaturated aldehydes.
  • Enantioenriched spiro nitrogen heterocycles via asymmetric nucleophilic epoxidation of α-ylideneoxindole esters.
  • Optically active secondary alcohols by asymmetric addition of Et2Zn to various aldehydes.

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