| Identification | Back Directory | [Name]
SR 58611A | [CAS]
121524-09-2 | [Synonyms]
SR 58611A
SR 58611A hydrochloride
Amibegron hydrochloride
[[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]ox]yaceticacidethylesterhydrochloride
Acetic acid, [[(7S)?-?7-?[[(2R)?-?2-?(3-?chlorophenyl)?-?2-?hydroxyethyl]?amino]?-?5,?6,?7,?8-?tetrahydro-?2-?naphthalenyl]?oxy]?-?, ethyl ester, hydrochloride (1:1) | [Molecular Formula]
C22H27Cl2NO4 | [MDL Number]
MFCD00886563 | [MOL File]
121524-09-2.mol | [Molecular Weight]
440.36 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble20mg/mL, clear | [form ]
powder | [color ]
white to beige | [optical activity]
[α]/D -75 to -95°, c = 0.5 in methanol |
| Hazard Information | Back Directory | [Uses]
SR 58611A is a selective β3-adrenergic receptor agonist with anxiolytic and antidepressant properties (1,2). SR 58611A is blood brain barrier permeable. | [Biochem/physiol Actions]
SR58611A is a potent, specific b3 adrenergic receptor agonist. The EC50 for reduction of β3-mediated spontaneous motility in rat distal colon sections is 3.5 nM. Minimal anti-depressant efficacious doses for SR58611A are 0.1-0.3 mpk in rodent models. | [storage]
Desiccate at RT |
|
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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BOC Sciences
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https://www.bocsci.com |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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