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129212-35-7

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129212-35-7 Structure

129212-35-7 Structure
IdentificationBack Directory
[Name]

8-EpitacroliMus
[CAS]

129212-35-7
[Synonyms]

8-EpitacroliMus
Tacrolmius 8-epimer
Tacrolimum 8-Epimer
Tacrolimus EP Impurity D
Tacrolimus 8-Epimer/8-epi Tacrolimus
Tacrolimus Impurity 1(Tacrolimus 8-Epimer)
Tacrolimus EP Impurity D (8-epi Tacrolimus)
Tacrolimus Impurity 1（Tacrolimus EP Impurity D）（Tacrolimus 8-Epimer）
[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8R*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]- 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-pro
15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8...
[Molecular Formula]

C44H69NO12
[MOL File]

129212-35-7.mol
[Molecular Weight]

804.02
Chemical PropertiesBack Directory
[Boiling point ]

871.7±75.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
[pka]

9.97±0.70(Predicted)
Safety DataBack Directory
[HS Code ]

2934990002
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Solid
[Uses]

8-Epitacrolimus is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. 8-Epitacrolimus is also an Epimer of Tacrolimus (F370000).
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