| Identification | Back Directory | [Name]
Fabesetron | [CAS]
129300-27-2 | [Synonyms]
Fabesetron
Fabesetron [INN]
Pyrido[1,2-a]indol-6(7H)-one, 8,9-dihydro-10-methyl-7-[(4-methyl-1H-imidazol-5-yl)methyl]-, (7R)- | [Molecular Formula]
C18H19N3O | [MDL Number]
MFCD00891468 | [MOL File]
129300-27-2.mol | [Molecular Weight]
293.36 |
| Hazard Information | Back Directory | [Definition]
ChEBI: Fabesetron is an organic heterotricyclic compound that is 8,9-dihydropyrido[1,2-a]indol-6(7H)-one substituted by a (5-methyl-1H-imidazol-4-yl)methyl group at position 7R and a methyl group at position 10. It is a dual 5-HT3 and 5-HT4 receptors antagonist whose clinical development was terminated in phase II. It was being developed for the treatment of chemotherapy-induced emesis and irritable bowel syndrome. It has a role as an antiemetic and a serotonergic antagonist. It is a member of imidazoles and an organic heterotricyclic compound. |
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