| Identification | Back Directory | [Name]
CbzNH-PEG4-CH2COOH | [CAS]
1451362-51-8 | [Synonyms]
CbzNH-PEG4-CH2COOH
3-Oxo-1-phenyl-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid
5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(phenylmethyl) ester | [Molecular Formula]
C18H27NO8 | [MDL Number]
MFCD30528569 | [MOL File]
1451362-51-8.mol | [Molecular Weight]
385.41 |
| Hazard Information | Back Directory | [Description]
CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine. |
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