| Identification | Back Directory | [Name]
BQ-788 | [CAS]
156161-89-6 | [Synonyms]
CS-1494
BQ-788 SODIUM
BQ789 Sodium Salt
1-ELAIDYLPHOSPHOCHOLINE, >97%
BQ788 SODIUM SALT; BQ 788 SODIUM SALT
BQ-788 SYNTHETIC >97% ETB ENDOTHELIN REC EPT
N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-
N-cis-2,6-dimethylpiperidinocarbonyl-L-γMeLeu-D-Trp(COOMe)-D-Nle-ONa
2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle
DMpc-gaMMa-MeLeu-D-Trp(1-CO2CH3)-D-Nle.Na (DMpc : cis-2,6-DiMethylpiperidinocarbonyl)
N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucinesodiumsalt
N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine sodium salt
sodium,(2R)-2-[[(2R)-2-amino-3-(1-methoxycarbonylindol-3-yl)propanoyl]-[(2S)-2-[[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino]-4,4-dimethylpentanoyl]amino]hexanoate
N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine sodium salt, 2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle | [Molecular Formula]
C34H50N5O7.Na | [MDL Number]
MFCD03095579 | [MOL File]
156161-89-6.mol | [Molecular Weight]
663.79 |
| Hazard Information | Back Directory | [Uses]
BQ-788 has been used as a selective endothelin-B (ETRB) blocker in human airway smooth muscle cells (HASMCs), uterine mesothelial cells (UtMCs)-derived vascular smooth muscle cells (VSMCs), and human umbilical vein endothelial cells (HUVECs) | [Biological Activity]
Potent, selective ET B receptor antagonist (IC 50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells). | [Biochem/physiol Actions]
Selective ETB endothelin receptor antagonist. | [storage]
+4°C |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
| Company Name: |
SPIRO PHARMA
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| Website: |
www.spiropharma.com.cn |
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