| Identification | Back Directory | [Name]
Autophinib | [CAS]
1644443-47-9 | [Synonyms]
CS-2834
Autophinib
6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-pyrimidinamine
6-CHLORO-N-(5-METHYL-1H-PYRAZOL-3-YL)-2-(4-NITROPHENOXY)PYRIMIDIN-4-AMINE
4-Pyrimidinamine, 6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)- | [Molecular Formula]
C14H11ClN6O3 | [MDL Number]
MFCD31560472 | [MOL File]
1644443-47-9.mol | [Molecular Weight]
346.73 |
| Chemical Properties | Back Directory | [Boiling point ]
640.6±65.0 °C(Predicted) | [density ]
1.547±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMSO:13.98(Max Conc. mg/mL);40.32(Max Conc. mM) | [form ]
A solid | [pka]
13.78±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Autophinib is a potent VPS34 inhibitor (IC50 = 19 nM). Inhibits starvation- and Rapamycin-induced autophagy (IC50 values = 40 and 90 nM, respectively). | [storage]
Store at +4°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|