| Identification | Back Directory | [Name]
PKTPKKAKKL | [CAS]
164669-07-2 | [Synonyms]
PKTPKKAKKL
CDK5 SUBSTRATE
CDK5 SUBSTRATE [PKTPKKAKKL]
ZSZMVAFYNVHXHA-BJSZDZKQSA-N
PRO-LYS-THR-PRO-LYS-LYS-ALA-LYS-LYS-LEU
H-PRO-LYS-THR-PRO-LYS-LYS-ALA-LYS-LYS-LEU-OH
L-Leucine, L-prolyl-L-lysyl-L-threonyl-L-prolyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl- | [Molecular Formula]
C53H99N15O12 | [MDL Number]
MFCD08459410 | [MOL File]
164669-07-2.mol | [Molecular Weight]
1138.45 |
| Chemical Properties | Back Directory | [Boiling point ]
1466.5±65.0 °C(Predicted) | [density ]
1.209±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
3.37±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 μM. |
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