Identification | Back Directory | [Name]
(6R)-6-[(3R,5S,7R,10S,13R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptanoic acid | [CAS]
17974-66-2 | [Synonyms]
-DihydroxycoprostanicAcid 3α,7α-Dihydroxycoprostanic Acid 3a,7a-Dihydroxycoprostanic acid 3α,7α-Dihydroxy-5β-cholest-26-oic acid 3α,7α-Dihydroxy-5β-cholestan-26-oic acid (25RS)-3α,7α-dihydroxy-5β-cholestan-26-oic acid (6R)-6-[(3R,5S,7R,10S,13R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptanoic acid | [Molecular Formula]
C27H46O4 | [MOL File]
17974-66-2.mol |
Hazard Information | Back Directory | [Uses]
3a,7a-Dihydroxycoprostanic Acid is a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3a,7a-Dihydroxycoprostanic Acid. | [Definition]
ChEBI: 3alpha,7alpha-dihydroxy-5beta-cholestan-26-oic acid is a cholestanoid that is 5beta-cholestan-26-oic acid substituted by alpha-hydroxy groups at positions 3 and 7 respectively. It has a role as a human metabolite and a mouse metabolite. It is a dihydroxy monocarboxylic acid, a 7alpha-hydroxy steroid, a 3alpha-hydroxy steroid and a cholestanoid. It derives from a hydride of a 5beta-cholestane. |
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MedChemExpress
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