| Identification | Back Directory | [Name]
Anhydrosafflor yellow B | [CAS]
184840-84-4 | [Synonyms]
AHSYB
Anhydrosafflor yellow B
(2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1
4(2H)-Benzofuranone, 7-β-D-glucopyranosyl-3-[3-β-D-glucopyranosyl-2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-6-oxo-1,4-cyclohexadien-1-yl]-3,7-dihydro-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-, (2S,3S)- | [Molecular Formula]
C48H52O26 | [MDL Number]
MFCD32644781 | [MOL File]
184840-84-4.mol | [Molecular Weight]
1044.92 |
| Hazard Information | Back Directory | [Description]
Safflower, also known as red and blue flower, thorn safflower, mainly contains compounds such as chalcone pigments, flavonoids, phenolic acids, steroids and polysaccharides. Among the safflower yellows, hydroxyl safflower yellow A and dehydrated safflower yellow B (AHSYB) have the highest content, which are the main active ingredients with physiological activity in safflower.Anhydrosafflor yellow B can improve heart and brain blood oxygen supply, reduce ischemic injury, anticoagulant, anti-myocardial ischemia, inhibit platelet aggregation, anti-oxidation, anti-tumor and anti-inflammation and other pharmacological effects. | [Biological Activity]
Anhydrosafflor yellow B (AHSYB) is a quinolone C-glycoside isolated from Carthamus tinctorius. It inhibits ADP-induced platelet aggregation, has significant antioxidant effects in vitro, and has antitoxic activity against H2O2-induced PC12 cells and primary neuronal cells. | [Synthesis]
A method for extracting and purifying dehydrated safflower yellow B in safflower, 1) using warm soaking method to obtain safflower water extract; 2) pretreatment of macroporous adsorption resin; 3) macroporous resin adsorption; 4) macroporous resin Pore resin elution. |
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