| Identification | Back Directory | [Name]
ABT-492 | [CAS]
189279-58-1 | [Synonyms]
WQ3034
CS-711
CS-2335
ABT-492
RX-3341
Delafloxacin
Delafloxacinum
ABT492/ABT-492
ABT-492(WQ-3034)
ABT-492/Delafloxacin
Delafloxacin, ABT-492
Delafloxacin Impurity
Delafloxacin Free Acid
DELAFLOXACIN;RX-3341;WQ-3034;ABT492
DELAFLOXACIN;DELAFLOXACINUM;RX-3341;WQ-3034;ABT492;ABT 492
DELAFLOXACINUM; RX-3341; WQ-3034; ABT492; ABT 492; ABT-492;WQ3034;WQ 3034
1-(6-aMino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
1-(6-Amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylic acid
1-(6-Amino-3,5-difluoro-pyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-quinolin-3-carboxylic acid
3-Quinolinecarboxylic acid, 1-(6-aMino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-
3-(6-Amino-3,5-difluoro-pyridin-2-ylamino)-2-{2,5-difluoro-4-[3-(3-methyl-2-oxo-butyl)-cyclobutyl]-benzoyl}-acrylic acid ethyl ester | [Molecular Formula]
C18H12ClF3N4O4 | [MDL Number]
MFCD09955301 | [MOL File]
189279-58-1.mol | [Molecular Weight]
440.76 |
| Chemical Properties | Back Directory | [Melting point ]
238-241℃ | [Boiling point ]
698.5±55.0 °C(Predicted) | [density ]
1.796 | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Very Slightly, Heated, Sonicated) | [form ]
powder | [pka]
5.49±0.50(Predicted) | [color ]
white to beige | [CAS DataBase Reference]
189279-58-1 |
| Hazard Information | Back Directory | [Uses]
Delafloxacin is a potent agent and broad-spectrum anionic fluoroquinolone against Streptococcus pneumoniae and diverse group of pathogens. | [Biochem/physiol Actions]
Delafloxacin is a fluoroquinolone antibiotic active against both Gram-negative and Gram-positive bacteria such as MRSA. Delafloxacin targets both DNA gyrase and topoisomerase IV, inhibiting DNA synthesis. Unlike most fluoroquinolones, delafloxacin is weakly acidic, which increases its potency in an acidic environments such as those existing in inflammatory cells and in skin and soft tissue infections. Delafloxacin shows good activity against most fluoroquinolone-resistant strains. | [storage]
Store at -20°C |
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