| Identification | Back Directory | [Name]
(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid | [CAS]
189684-50-2 | [Synonyms]
N-ACETYL-ASP-GLU-VAL-ASP-PNA
L-α-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-
N-Acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-N-(4-nitrophenyl)-L-alpha-asparagine
(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid | [Molecular Formula]
C26H34N6O13 | [MOL File]
189684-50-2.mol | [Molecular Weight]
638.59 |
| Chemical Properties | Back Directory | [Boiling point ]
1187.0±65.0 °C(Predicted) | [density ]
1.448±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Acetonitrile:Methanol (1:1): 1 mg/ml | [form ]
A crystalline solid | [pka]
4.03±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (Km = 18, 11, 32, 180, and 12 μM for caspases-1, -3, -4, -6, and -7, respectively). It is not cleaved by caspase-2. Cleavage is monitored colorimetrically at 405 nm. | [storage]
Store at -20°C |
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
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