| Identification | Back Directory | [Name]
5(S)-HETRE | [CAS]
195061-94-0 | [Synonyms]
5(S)-HETRE
5(S)HETrE,5(S) HETrE
LSADDRSUZRRBAN-FDSUASFTSA-N
5S-HYDROXY-6E,8Z,11Z-EICOSATRIENOIC ACID | [Molecular Formula]
C20H34O3 | [MDL Number]
MFCD00216110 | [MOL File]
195061-94-0.mol | [Molecular Weight]
322.48 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml |
| Hazard Information | Back Directory | [Description]
5(S)-HETrE is produced by the action of 5-LO when mead acid is the substrate.1,2 There are no literature reports of the biological activity or further metabolic fate of 5(S)-HETrE. | [Definition]
ChEBI: 5(S)-HETrE is a 5-HETrE consisting of (6E,8Z,11Z)-icosatrienoic acid in which the 5-hydroxy group has S-configuration. It has a role as a human xenobiotic metabolite. | [References]
1. Jakschik, B.A., Sams, A.R., Sprecher, H., et al. Fatty acid structural requirements for leukotriene biosynthesis Prostaglandins 20,401-410(1980).
2. Jakschik, B.A., Morrison, A.R., and Sprecher, H. Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway J. Biol. Chem. 258,12797-12800(1983). |
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