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201304-22-5

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201304-22-5 Structure

201304-22-5 Structure
IdentificationBack Directory
[Name]

4-[4-[4-(AMINOIMINOMETHYL)PHENYL]-1-PIPERAZINYL]-1-PIPERIDINEACETIC ACID TRIHYDROCHLORIDE
[CAS]

201304-22-5
[Synonyms]

GR1440533HCl
GR 144053 trihydroch
GR 144053 TRIHYDROCHLORIDE
GR 144053 TRIHYDROCHLORIDE HYDRATE
4-[4-[4-(AMINOIMINOMETHYL)PHENYL]-1-PIPERAZINYL]-1-PIPERIDINEACETIC ACID TRIHYDROCHLORIDE
4-[4-[4-(aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride hydrate
[Molecular Formula]

C18H30Cl3N5O2
[MDL Number]

MFCD06798360
[MOL File]

201304-22-5.mol
[Molecular Weight]

454.82
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: 23 mg/mL
[form ]

solid
[color ]

brown
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H315-H335
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

GR 144053 Trihydrochloride is a glycoprotein IIb/IIIa (integrin αIIbβ3) receptor antagonist. Antithrombotic.
[Biological Activity]

A potent and selective platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC 50 = 37 nM). Orally active and highly effective at inhibiting thrombus formation in vivo .
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