ChemicalBook--->CAS DataBase List--->209253-67-8

209253-67-8

209253-67-8 Structure

209253-67-8 Structure
IdentificationBack Directory
[Name]

Eplerenone EP Impurity A
[CAS]

209253-67-8
[Synonyms]

Eplerenone Impurity A
Eplerenone EP Impurity A
Eplerenone Impurity 6(Eplerenone EP Impurity A)
(7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone
(2''S)-3'',4''-Dihydro-3,5''-dioxospiro[androst-4-ene-17,2′-furan]-7α,9α-carbolactone
Pregn-4-ene-7,21-dicarboxylic acid, 9,17-dihydroxy-3-oxo-, 7,9:21,17-dilactone, (7α,17α)-
[Molecular Formula]

C23H28O5
[MOL File]

209253-67-8.mol
[Molecular Weight]

384.47
Chemical PropertiesBack Directory
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

(7a,17a)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone is an eplerenone (E588775) impurity. Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
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