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2154-02-1

2154-02-1 Structure

2154-02-1 Structure
IdentificationBack Directory
[Name]

Metofoline
[CAS]

2154-02-1
[Synonyms]

NIH 7672
Versidyne
ARC I-K-1
ARC-1-K-1
Metofoline
Metopholine
Methopholine
1-[2-(4-chlorophenyl)ethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
Isoquinoline, 1-[2-(4-chlorophenyl)ethyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-2-Methyl-
[Molecular Formula]

C20H24ClNO2
[MDL Number]

MFCD00864337
[MOL File]

2154-02-1.mol
[Molecular Weight]

345.86
Chemical PropertiesBack Directory
[Melting point ]

110-111°
[density ]

1.0715 (rough estimate)
[refractive index ]

1.5400 (estimate)
Hazard InformationBack Directory
[Uses]

Analgesic.
[Definition]

ChEBI: Metofoline is a member of isoquinolines.
[Brand name]

R 4-1778/1.
[World Health Organization (WHO)]

Metofoline, an analgesic, was introduced in the early 1960s for the treatment of mild to moderate acute and chronic pain. It was never available outside the USA.
Safety DataBack Directory
[Toxicity]

LD50 in mice, rats (mg/kg): 180, 400 s.c.; 180, 400 orally; 70, 100 i.p.; in mice, rabbits (mg/kg): 70, 30 i.v. (Brossi, 1965)
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