| Identification | Back Directory | [Name]
K-604 dihydrochloride | [CAS]
217094-32-1 | [Synonyms]
K-604 2HCl
K-604
(K604)
K-604 >=98% (HPLC)
K-604 dihydrochloride | [Molecular Formula]
C23H31ClN6OS3 | [MOL File]
217094-32-1.mol | [Molecular Weight]
539.17 |
| Hazard Information | Back Directory | [Biological Activity]
K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with IC50 of 0.45±0.06 μM. | [in vivo]
Using F1B hamsters, an animal model susceptible to diet-induced hyperlipidemia and atherosclerosis, the effects of K-604 dihydrochloride on aortic lesion areas and plasma cholesterol levels are assessed. | [target]
| ACAT-1 < span> 0.45 μM (IC 50 ) | ACAT-2 102.85 μM (IC 50 ) | | [storage]
Store at -20°C |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|