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2239272-16-1

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2239272-16-1 Structure

2239272-16-1 Structure
IdentificationBack Directory
[Name]

AWZ1066S
[CAS]

2239272-16-1
[Synonyms]

AWZ1066S
AWZ1066S;AWZ-1066S;AWZ 1066S
2-[(3S)-3-Methyl-4-morpholinyl]-N-[[2-(trifluoromethyl)-3-pyridinyl]methyl]pyrido[2,3-d]pyrimidin-4-amine
Pyrido[2,3-d]pyrimidin-4-amine, 2-[(3S)-3-methyl-4-morpholinyl]-N-[[2-(trifluoromethyl)-3-pyridinyl]methyl]-
[Molecular Formula]

C19H19F3N6O
[MDL Number]

MFCD31813769
[MOL File]

2239272-16-1.mol
[Molecular Weight]

404.39
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (309.11 mM; Need ultrasonic)
Hazard InformationBack Directory
[Biological Activity]

AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis, with an EC50 of 2.5 nM in cell assay[1].
[References]

[1]. Hong WD, et al. AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1414-1419.
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