| Identification | Back Directory | [Name]
RAF mutant-IN-1 | [CAS]
2340020-82-6 | [Synonyms]
RAF MUTANT-IN-1
RAF mutant IN 1,RAF mutantIN1 | [Molecular Formula]
C23H17Cl2FN6O2S | [MDL Number]
MFCD32201092 | [MOL File]
2340020-82-6.mol | [Molecular Weight]
531.39 |
| Hazard Information | Back Directory | [Description]
RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
C-RAF 340D/Y341D|21 nM (IC50)|B-RafV600E|30 nM (IC50)|BRAFWT|392 nM (IC50)
| [storage]
Store at -20°C | [References]
[1]. BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1. |
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