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2378173-15-8

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2378173-15-8 Structure

2378173-15-8 Structure
IdentificationBack Directory
[Name]

Cyclohexanecarboxylic acid, 2-[[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]amino]-, (1R,2S)-
[CAS]

2378173-15-8
[Synonyms]

Cyclohexanecarboxylic acid, 2-[[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]amino]-, (1R,2S)-
[Molecular Formula]

C20H20N4O4
[MDL Number]

MFCD31697699
[MOL File]

2378173-15-8.mol
[Molecular Weight]

380.4
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 30 mg/ml
[form ]

A solid
Hazard InformationBack Directory
[Biological Activity]

PF-06928215 is a high-affinity cGAS (cyclic GMP-AMP Synthase) inhibitor with IC50 of 4.9 μM and affinity Kd value of 0.2 μM.
[in vitro]

PF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression.

[storage]

Store at -20°C
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