| Identification | Back Directory | [Name]
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol | [CAS]
289893-25-0 | [Synonyms]
arimoclomol
Amrioclomol
Pefcalcitol
BRX-220 free base
(2R-)Arimoclomol NEW
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide | [Molecular Formula]
C14H20ClN3O3 | [MDL Number]
MFCD16660939 | [MOL File]
289893-25-0.mol | [Molecular Weight]
313.78 |
| Chemical Properties | Back Directory | [Melting point ]
93 - 95o C | [Boiling point ]
539.2±60.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.03±0.20(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Arimoclomol is a co-inducer of HSP that acts through heat shock factor 1 (HSF1) in cells undergoing cellular stress. Has therapeutic potential in motor neuron degenerative diseases. Potential treatment for liposomal storage disorders, such as Niemann-Pick disease type C. |
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
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