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30100-16-4

30100-16-4 Structure

30100-16-4 Structure
IdentificationBack Directory
[Name]

BOC-8-AMINOCAPRYLIC ACID
[CAS]

30100-16-4
[Synonyms]

BOC-8-AOC-OH
BOC-AOC(8)-OH
BOC-NH-(CH2)7-COOH
RARECHEM EM WB 0025
BOC-AMINOCAPRYLIC ACID
Boc-8-aminooctanoicaci
BOC-8-AMINOCAPRYLIC ACID
BOC-8-AMINOOCTANOIC ACID
8-(BOC-AMINO)CAPRYLIC ACID
8-(BOC-AMINO)OCTANOIC ACID
N-Boc-8-amino-octanoic acid
(Tert-Butoxy)Carbonyl 8-Aoc-OH
BOC-8-AMINOCAPRYLIC ACID USP/EP/BP
Boc-8-aminocaprylic acid≥ 97% (HPLC)
T-BUTOXYCARBONYL-8-AMINOCAPRYLIC ACID
T-BUTOXYCARBONYL-8-AMINOOCTANOIC ACID
N-T-BUTYLOXYCARBONYL-8-AMINO-OCTANOIC ACID
N-TERT-BUTYLOXYCARBONYL-8-AMINO-OCTANOIC ACID
Boc-8-aminooctanoic acid (Boc-aminocaprylic acid)
8-[[(1,1-dimethylethoxy)carbonyl]amino]Octanoic acid
Octanoicacid, 8-[[(1,1-dimethylethoxy)carbonyl]amino]-
8-(Boc-amino)caprylic acid, 8-(Boc-amino)octanoic acid
[Molecular Formula]

C13H25NO4
[MDL Number]

MFCD00270350
[MOL File]

30100-16-4.mol
[Molecular Weight]

259.34
Chemical PropertiesBack Directory
[Melting point ]

56-59 °C
[Boiling point ]

406.0±28.0 °C(Predicted)
[density ]

1.036±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[pka]

4.78±0.10(Predicted)
[BRN ]

2268966
Safety DataBack Directory
[WGK Germany ]

3
[HazardClass ]

IRRITANT
[HS Code ]

29241990
Hazard InformationBack Directory
[Description]

Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
[Chemical Properties]

White amorphous powder
[Uses]

Reagent to introduce a protected w-amino alkyl spacer. Longer spacer arms often impart increased activity to the substrate
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