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31993-01-8

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31993-01-8 Structure

31993-01-8 Structure
IdentificationBack Directory
[Name]

SIB 1757
[CAS]

31993-01-8
[Synonyms]

SIB 1757
6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL
6-methyl-2-[(E)-phenyldiazenyl]pyridin-3
3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)-
6-Methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol
(E)-6-Methyl-2-(phenyldiazenyl)pyridin-3-ol
SIB-1757 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL
[Molecular Formula]

C12H11N3O
[MDL Number]

MFCD00506102
[MOL File]

31993-01-8.mol
[Molecular Weight]

213.24
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

crystalline
[color ]

red
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

SIB 1757 is an antagonist for mGluR-5.
[Definition]

ChEBI: 6-methyl-2-(phenylhydrazinylidene)-3-pyridinone is a member of phenylhydrazines.
[Biological Activity]

A highly selective antagonist for the mGlu 5 metabotropic glutamate receptor subtype; displays an IC 50 value of 0.4 μ M at hmGlu 5 compared with > 30 μ M at hmGlu 1b , hmGlu 2 , hmGlu 4 , hmGlu 6 , hmGlu 7 and hmGlu 8 .
Spectrum DetailBack Directory
[Spectrum Detail]

SIB 1757(31993-01-8)1HNMR
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