| Identification | Back Directory | [Name]
dextilidine | [CAS]
32447-90-8 | [Synonyms]
dextilidine
2α-(Dimethylamino)-1-phenyl-3-cyclohexene-1β-carboxylic acid ethyl ester
2α-(Dimethylamino)-1α-phenyl-3-cyclohexene-1β-carboxylic acid ethyl ester
(1R,2R)-2-(Dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylic acid ethyl ester
(1S,2S)-2-(Dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylic acid ethyl ester
3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, (1S,2R)- | [EINECS(EC#)]
251-048-6 | [Molecular Formula]
C17H23NO2 | [MDL Number]
MFCD00868712 | [MOL File]
32447-90-8.mol | [Molecular Weight]
273.37 |
| Hazard Information | Back Directory | [Definition]
ChEBI: Dextilidine is an ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate that has S configuration at the carbon bearing the phenyl group and R configuration at the carbon bearing the dimethylamino group. The opioid analgesic tilidine is the racemate comprising equimolar amounts of dextilidine and its enantiomer, ent-dextilidine. A prodrug, tilidine is converted by the liver to the active analgesic, nortilidine; virtually all of the opioid activity resides in the (1S,2R) isomer (i.e. the isomer derived from dextilidine). It has a role as an opioid analgesic and a prodrug. It is an enantiomer of an ent-dextilidine. |
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