| Identification | Back Directory | [Name]
4-OXO-1,4-DIHYDRO-[1,10]PHENANTHROLINE-3-CARBOXYLIC ACID | [CAS]
331830-20-7 | [Synonyms]
4-DPCA
1,4-DPCA
TVBAVFFTADCWKG-UHFFFAOYSA-N
4-OXO-1,4-DIHYDRO-[1,10]PHENANTHROLINE-3-CARBOXYLIC ACID | [Molecular Formula]
C13H8N2O3 | [MDL Number]
MFCD07357380 | [MOL File]
331830-20-7.mol | [Molecular Weight]
240.21 |
| Questions And Answer | Back Directory | [biological activity]
1,4-DPCA, a potent and selective inhibitor of prolyl-4-hydroxylase, is also an inhibitor of collagen hydroxylation in chemicalbook cells of human foreskin fibroblasts with IC50 of 2.4µM. 1,4-DPCA inhibits the alpha isoform of prolyl-4-hydroxylase and stabilizes HIF-1alpha protein. |
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InvivoChem
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