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333745-53-2

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333745-53-2 Structure

333745-53-2 Structure
IdentificationBack Directory
[Name]

LX-2343
[CAS]

333745-53-2
[Synonyms]

LX-2343
LX2343;LX-2343;LX 2343
2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(1,3-benzodioxol-5-yl)acetamide
Acetamide, N-1,3-benzodioxol-5-yl-2-[(5-chloro-2-methoxyphenyl)(phenylsulfonyl)amino]-
[Molecular Formula]

C22H19ClN2O6S
[MDL Number]

MFCD02578482
[MOL File]

333745-53-2.mol
[Molecular Weight]

474.91
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:73.33(Max Conc. mg/mL);154.41(Max Conc. mM)
DMF:33.0(Max Conc. mg/mL);69.49(Max Conc. mM)
[form ]

A solid
Hazard InformationBack Directory
[Uses]

LX-2343, is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. It has also shown activity as a non-ATP competitive PI3K inhibitor. LX2343 stimulates autophagy in its promotion of Aβ clearance.
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