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366454-36-6

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366454-36-6 Structure

366454-36-6 Structure
IdentificationBack Directory
[Name]

EB-47
[CAS]

366454-36-6
[Synonyms]

EB-47
EB 47 DIHYDROCHLORIDE
PARP Inhibitor IX, EB-47
5'-Deoxy-5'-[4-[2-[(2,3-dihydro-1-oxo-1H-isoindol-4-yl)aMino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine Dihydrochloride
4-[1-(6-AMino-9H-purin-9-yl)-1-deoxy-β-D- ribofuranuronoyl]-N-(2,3-dihydro-1-oxo-1H-isoindol-4-yl)-1-piperazineacetaMide Dihydrochloride
[Molecular Formula]

C24H27N9O6
[MDL Number]

MFCD30478803
[MOL File]

366454-36-6.mol
[Molecular Weight]

537.53
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

H2O: 10 mg/mL, soluble
[form ]

solid
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

EB 47 is a potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Poly(ADP-ribose) polymerases (PARPs) play a major role in cellular survival and maintenance of energy stores after genotoxic insu lt.
[Uses]

EB 47 is a potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Poly(ADP-ribose) polymerases (PARPs) play a major role in cellular survival and maintenance of energy stores after genotoxic insult.
Spectrum DetailBack Directory
[Spectrum Detail]

EB-47(366454-36-6)1HNMR
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