ChemicalBook--->CAS DataBase List--->37308-75-1

37308-75-1

37308-75-1 Structure

37308-75-1 Structure
IdentificationBack Directory
[Name]

FLAVOKAWAINC
[CAS]

37308-75-1
[Synonyms]

FLAVOKAWAINC
Flavokavin C
Flavokavain C
(E)-2',4-Dihydroxy-4',6'-dimethoxychalcone
4,2'-Dihydroxy-4',6'-dimethoxy-trans-chalcone
2',4-Dihydroxy-4',6'-dimethoxy-trans-chalcone
(E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-
[Molecular Formula]

C17H16O5
[MDL Number]

MFCD00016489
[MOL File]

37308-75-1.mol
[Molecular Weight]

300.31
Chemical PropertiesBack Directory
[Melting point ]

179-182 °C
[Boiling point ]

556.0±50.0 °C(Predicted)
[density ]

1.279±0.06 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO: 12.5 mg/mL (41.62 mM)
[pka]

6.91±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Flavokawain C?is a?chalcone found in the kava plant. Studies showed that?Flavokawain C can inhibit cell cycle and promote apoptosis in HCT 116 cells. In addition, natural chalcones have been?implicated as lead compounds for developing dual inhibitors against?Histone deacetylase enzymes (HDACs) and NF-κB. Flavokawain C is a related compound Flavokawain A (F371020).
[Definition]

ChEBI: Flavokawain C is a member of chalcones.
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