ChemicalBook--->CAS DataBase List--->38315-43-4

38315-43-4

38315-43-4 Structure

38315-43-4 Structure
IdentificationBack Directory
[Name]

17-PHENYL TRINOR PROSTAGLANDIN E2
[CAS]

38315-43-4
[Synonyms]

CL 116147
17-Phenyl-omega-trinor-PGE2
FOBVMYJQWZOGGJ-XYRJXBATSA-N
17-Phenyl-18,19,20-trinor-PGE2
17-Phenyltrinorprostaglandinee2
17-PHENYL TRINOR PROSTAGLANDIN E2
17-PHENYL-TRINOR-PROSTAGLANDIN E2 98%
17-PHENYL TRINOR PROSTAGLANDIN E2 99+%
17-Phenyl-18,19,20-trinorprostaglandin E2
7-[3-hydroxy-2-(3-hydroxy-5-phenylpent-1-enyl)-5-oxocyclopentyl]hept-5-enoic acid
9-OXO-11ALPHA-15S-DIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-5-oxocyclopentyl]-, (5Z)-
[Molecular Formula]

C23H30O5
[MDL Number]

MFCD00135219
[MOL File]

38315-43-4.mol
[Molecular Weight]

386.48
Chemical PropertiesBack Directory
[Boiling point ]

597.1±50.0 °C(Predicted)
[density ]

1?+-.0.06 g/cm3(Predicted)
[RTECS ]

MJ9681060
[solubility ]

DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol); Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >0.8 mg/ml (from 17-phenyl tri
[form ]

Oil
[pka]

4.75±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS08
[Signal word ]

Warning
[Hazard statements ]

H302-H360
[Precautionary statements ]

P201-P280-P301+P312a-P308+P313-P405-P501a
Hazard InformationBack Directory
[Uses]

17-Phenyl-trinor-prostaglandin E2 is a synthetic analog of PGE2 and an agonist at the EP1 and EP3 receptor (1). Prostaglandin E2(PGE2) regulates neuroinflammatory responses and is upregulated in brain injury by cyclooxygenase 2 (COX-?2) and membrane-bound PGE synthase. 17-Phenyl-trinor-prostaglandin E2 can be used to investigate inflammatory signaling pathways (2).
[Definition]

ChEBI: 17-phenyl-18,19,20-trinor-prostaglandin E2 is a prostanoid that is 18,19,20-trinor-prostaglandin E2 in which one of the terminal methyl hydrogens has been replaced by a phenyl group. It has a role as a human metabolite and a prostaglandin receptor agonist. It is a prostanoid, an alicyclic ketone, a beta-hydroxy ketone, a secondary alcohol, an oxo monocarboxylic acid, a hydroxy monocarboxylic acid and an olefinic compound.
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