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40252-74-2

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40252-74-2 Structure

40252-74-2 Structure
IdentificationBack Directory
[Name]

DMEOB
[CAS]

40252-74-2
[Synonyms]

DMEOB
bis(3-methoxybenzylidene)hydrazine
[(3-METHOXYPHENYL)METHYLENE]HYDRAZONE-3-METHOXYBENZALDEHYDE
3-METHOXYBENZALDEHYDE [(3-METHOXYPHENYL)METHYLENE]HYDRAZONE
Benzaldehyde, 3-methoxy-, 2-[(3-methoxyphenyl)methylene]hydrazone
[Molecular Formula]

C16H16N2O2
[MDL Number]

MFCD01001892
[MOL File]

40252-74-2.mol
[Molecular Weight]

268.31
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

H2O: insoluble
[form ]

solid
[color ]

yellow
Safety DataBack Directory
[Hazard Codes ]

Xi,N
[Risk Statements ]

41-50/53
[Safety Statements ]

26-36/37/39-60-61
[RIDADR ]

UN 3077 9/PG 3
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s.
[Biological Activity]

Negative allosteric modulator of the metabotropic glutamate receptor mGlu 5 ; displays reversible non-competitive inhibition of mGlu 5 -mediated responses (IC 50 = 3 μ M).
[Biochem/physiol Actions]

Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.
[storage]

Store at RT
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