Log in | Join Free | china | japan | germany
ChemicalBook--->CAS DataBase List--->480-76-2

480-76-2

Request For Quotation
480-76-2 Structure

480-76-2 Structure
IdentificationBack Directory
[Name]

JACOLINE
[CAS]

480-76-2
[Synonyms]

Jacolin
JACOLINE
(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
[Molecular Formula]

C18H27NO7
[MOL File]

480-76-2.mol
[Molecular Weight]

369.41
Chemical PropertiesBack Directory
[Melting point ]

221°C
Hazard InformationBack Directory
[Description]

A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.
[Uses]

Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).
[References]

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)
480-76-2 suppliers list
Company Name: Shaanxi Didu New Materials Co. Ltd
Tel: +86-89586680 +86-13289823923 , +86-13289823923
Website: www.dideu.com/en/
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Website: http://www.amadischem.com
Company Name: Wuxi Zhongkun Biochemical Technology Co., Ltd.  
Tel: 0510-85629785 18013409632
Website: www.reading-chemicals.com
Company Name: Wuhan ChemFaces Biochemical Co., Ltd.  
Tel: 18607101326 15172504745
Website: http://www.chemfaces.com
Company Name: Biyu Biotechnology (Shanghai) Co., ltd  
Tel: 021-26018599
Website: www.chemicalbook.com/ShowSupplierProductsList17160/0.htm
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Website: www.emmx.com
Company Name: Shenzhen Regent Biochemical Technology Co., Ltd.  
Tel: 0755-0755-85201366 18938635012
Website: www.regentsciences.com/
Company Name: Nanjing Digger Medical Technology Co. Ltd.  
Tel: 025-025-51191215 18013836722
Website: http://www.biaozhunpin.cn
Company Name: Sichuan BioCrick Biotech Co., Ltd  
Tel: 28-85433893
Website: www.biocrick.com
Company Name: Wuxi Helen Biotechnology Co., Ltd.,  
Tel: 0510-85629785 18013409632
Website: http://www.reading-chemicals.com
Company Name: TCI (Shanghai) Chemical Trading Co., Ltd.  
Tel: 021-61109150
Website: www.tcisct.com
Company Name: Foshan Treasure Biotechnology Co., Ltd  
Tel: 0757-85921206 18520245316
Website: http://www.fsbn-bio.com/
Company Name: Shanghai Moqi Biological Technology Co., LTD  
Tel: 021-38218169 13341702378
Website: www.winherb.cn
Company Name: Naturewill Biotechnology Co., Ltd.  
Tel: 18113192475 18113192475
Website: www.chemicalbook.com/supplier/24868677/
Company Name: Carbosynth  
Tel: +86 512 6260 5585
Website: www.carbosynth.com
Company Name: United States Biological  
Tel: 800.520.3011 or 781.639.5092
Website: www.usbio.net
Company Name: Shanghai Hao Zhun Biological Technology Co., Ltd.  
Tel: 15800340161
Website: www.zzsrm.com
Tags:480-76-2 Related Product Information