| Identification | Back Directory | [Name]
(+/-)-11-HYDROXY-12E,14Z-EICOSADIENOIC ACID | [CAS]
5598-37-8 | [Synonyms]
(+/-)11-HEDE
HDMIRVFIVOGVIC-YTLDOUCOSA-N
(+/-)-11-HYDROXY-12E,14Z-EICOSADIENOIC ACID
(+/-)-11-HYDROXY-12E,14Z-EICOSADIENOIC ACID
12,14-Eicosadienoic acid, 11-hydroxy-, (12E,14Z)- | [Molecular Formula]
C20H36O3 | [MDL Number]
MFCD00216105 | [MOL File]
5598-37-8.mol | [Molecular Weight]
324.5 |
| Hazard Information | Back Directory | [Description]
(±)11-HEDE is a racemic mixture of the monohydroxy fatty acids 11(S)-HEDE and 11(R)-HEDE . 11-HEDE is formed from eicosadienoic acid by cyclooxygenase (COX) and in macrophages.1,2 | [References]
1. Hemler, M.E., Crawford, C.G., and Lands, W.E.M. Lipoxygenation activity of purified prostaglandin-forming cyclooxygenase Biochemistry 17(9),1772-1779(1978).
2. Rabinovitch, H., Durand, J., Gualde, N., et al. Metabolism of polyunsaturated fatty acids by mouse peritoneal macrophages: The lipoxygenase metabolic pathway Agents Actions 11(6-7),580-583(1981). |
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