| Identification | Back Directory | [Name]
SULINDAC SULFONE | [CAS]
59973-80-7 | [Synonyms]
FGN-1
APTOSYN
Prevatec
EXISULIND
Ccris 7242
Unii-K619iig2R9
SULINDAC SULFONE
APTOSYN/EXISULIND
Sulindac Impurity B
(Z)-Sulindac Sulfone
Sulindac USP Related Compound B
Sulindac EP Impurity B (Sulindac Sulfone)
Sulindac Impurity 2（Sulindac EP Impurity B）
Sulindac EP Impurity B (Sulindac USP Related Compound B, Sulindac Sulfone)
Sulindac EP Impurity B/ Sulindac Related Compound B ((Z)-Sulindac Sulfone)
(Z)-5-FLUORO-2-METHYL-1[P-(METHYLSULFONYL)BENZYLIDENE]INDENE-3-ACETIC ACID
cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid
5-Fluoro-2-methyl-1-[(Z)-4-(methylsulfonyl)benzylidene]-1H-indene-3-acetic acid
(Z)-5-Fluoro-2-Methyl-1-[[4-(Methylsulfonyl)phenyl]Methylene]-1H-indene-3-acetic Acid
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfonyl)phenyl)methylene)-, (1Z)-
Sulindac Related Compound B ((Z)-2-{5-fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3- (1642020) | [Molecular Formula]
C20H17FO4S | [MDL Number]
MFCD01317811 | [MOL File]
59973-80-7.mol | [Molecular Weight]
372.41 |
| Chemical Properties | Back Directory | [Melting point ]
248-250°C | [alpha ]
D -62° (c = 1 in CHCl3) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO: >25 mg/mL | [form ]
solid | [color ]
yellow | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
An active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis. | [Uses]
Sulindac Sulfone is an inhibitor of growth and inducer of apoptosis in cancer cell lines. | [Definition]
ChEBI: A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor. |
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| Company Name: |
LGM Pharma
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| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
TOSUN PHARM
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| Tel: |
020-61855200 13326451905 |
| Website: |
www.toref.cn/ |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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