| Identification | Back Directory | [Name]
Azeliragon | [CAS]
603148-36-3 | [Synonyms]
TTP488
TTP-488
CS-2071
TTP 488
CRL 40G
AZELIRAGON
PF04494700
PF-04494700
PF 04494700
PF-04494700,TTP488
Azeliragon (TTP488)
Azeliragon(PF-04494700,TTP488)
PF04494700;TTP-488;PF 04494700;TTP 488;PF-04494700;TTP488
3--4--2-Butyl-1--4--4-chlorphenoxy-phenyl--1H-imidazol-4-yl-phenoxy--N-N-diethylpropan-1-amin
3-(4-{2-Butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl-amine
3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amine
N-[3-[4-[2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]propyl]-N,N-diethylamine
1-PropanaMine, 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-iMidazol-4-yl]phenoxy]-N,N-diethyl- | [Molecular Formula]
C32H38ClN3O2 | [MDL Number]
MFCD11977600 | [MOL File]
603148-36-3.mol | [Molecular Weight]
532.12 |
| Chemical Properties | Back Directory | [Boiling point ]
667.7±65.0 °C(Predicted) | [density ]
1.11±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:50.33(Max Conc. mg/mL);94.58(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);9.4(Max Conc. mM)
DMF:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.62(Max Conc. mM)
Ethanol:50.5(Max Conc. mg/mL);94.9(Max Conc. mM) | [form ]
A crystalline solid | [pka]
10.16±0.25(Predicted) |
| Hazard Information | Back Directory | [Biological Activity]
Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule inhibitor that inhibits the receptor for advanced glycation end products (RAGE). RAGE is an immunoglobulin-like cell surface receptor that is overexpressed in the brains of Alzheimer's patients. | [target]
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Tags:603148-36-3
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