| Identification | Back Directory | [Name]
1-NAPHTHOHYDROXAMIC ACID | [CAS]
6953-61-3 | [Synonyms]
NSC 57457
Naphthohydroxamicacid
1-NAPHTHOHYDROXAMIC ACID
a-Naphthohydroxamic acid
alpha-naphthohydroxamicacid
1-NAPHTHOHYDROXAMIC ACID 98+%
HDAC Inhibitor XIX, Compound 2
1-Naphthalenecarbohydroximic acid
n-hydroxy-1-naphthalenecarboxamid
N-HYDROXYNAPHTHALENE-1-CARBOXAMIDE
Naphthalene-1-carbohydroximic acid
N-Hydroxy-1-naphthalenecarboxamide | [Molecular Formula]
C11H9NO2 | [MDL Number]
MFCD00059546 | [MOL File]
6953-61-3.mol | [Molecular Weight]
187.19 |
| Hazard Information | Back Directory | [Uses]
1-Naphthohydroxamic Acid is a potent HDAC inhibitor with efficacy against HDAC8, HDAC1 and HDAC6. | [Biochem/physiol Actions]
1-Naphthohydroxamic Acid is a cell-permeable, potent, and selective histone deacetylase 8 (HDAC8) inhibitor. 1-Naphthohydroxamic acid selectively inhibits HDAC8 (IC50 = 14 μM) over class I HDAC1 and class II HDAC6 (IC50 >100 μM). Treatment of cells with 1-Naphthohydroxamic acid does not increase neither global histone H4 nor tubulin acetylation . Also in contrast to the pan-HDAC inhibitors the compound is not reducing total intracellular HDAC activity. | [storage]
Store at -20°C |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Tel: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0.htm |
| Company Name: |
TCI Europe
|
| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
| Company Name: |
TCI AMERICA
|
| Tel: |
800-4238616 |
| Website: |
https://www.tcichemicals.com/en/us/index.html |
|