| Identification | Back Directory | [Name]
(3b,6a,12b,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside | [CAS]
69884-00-0 | [Synonyms]
GINSENOSIDE A1
PSEUDOGINSENOSIDE
Pseuginsenoside F11
Pseuginsensoside F11
Pseudoginsenoside FII
PSEUDOGINSENOSIDE F11
PseudoGinsenoside F11 ,98%
(24R)-Pseudoginsenoside F11
(3b,6a,12b,24R)-20,24-Epoxy-3,12,25-
Pseudoginsenoside F11 (Ginsenoside A1)
Pseudoginsenoside F11, 98%, from Panax ginseng C. A. Mey.
PSEUDOEPHEDRINE HCl, (+)-1S,2S- AMP 1.0mg/ml(P)(DISCONTINUED)
(20S,24R)-6α-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)-20,24-epoxy-5α-dammarane-3β,12β,25-triol
[(24R)-20,24-Epoxy-3β,12β,25-trihydroxy-5α-dammaran-6α-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
(3b,6a,12b,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
(3β,6α,12β,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
β-D-Glucopyranoside, (3β,6α,12β,24R)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-
(3b,6a,12b,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
17β-[[(2S)-2β-Methyl-5α-(1-hydroxy-1-methylethyl)tetrahydrofuran]-2-yl]-3β,12β-dihydroxy-4,4,8β,10β,14α-pentamethyl-5α-gonane-6α-yl 2-O-α-L-rhamnopyranosyl-β-D-glucopyranoside
2-[[2-[[(3S,6S,8R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S,5R)-5-(2-hydroxypropan-2-yl)-2-methyl-2-oxolanyl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenan
(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S,5R)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol | [Molecular Formula]
C42H72O14 | [MDL Number]
MFCD00803938 | [MOL File]
69884-00-0.mol | [Molecular Weight]
801.01 |
| Chemical Properties | Back Directory | [Melting point ]
>196°C (dec.) | [Boiling point ]
885.3±65.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Methanol (Slightly), Pyridine (Slightly) | [form ]
neat | [pka]
12.85±0.70(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Description]
Pseudoginsenoside F11 is an ocotillol-type ginsenoside that has been found in P. ginseng and has diverse biological activities.1,2,3,4 In vivo, pseudoginsenoside F11 (10 mg/kg) prevents tubular cell apoptosis, decreases in renal glutathione peroxidase (GPX) and superoxide dismutase (SOD) levels, and increases in renal lipid peroxide levels in a rat model of nephrotoxicity induced by cisplatin (Item No. 13119).1 It reduces infarct size, brain water content, and cortical accumulation of autophagosomes in a rat model of ischemic stroke induced by permanent middle cerebral artery occlusion.2 Pseudoginsenoside F11 (4 and 8 mg/kg) inhibits morphine-induced memory impairment in the Morris water maze and development of morphine-induced conditioned place preference in mice.3 It also reduces hippocampal advanced glycation end product (AGE) and malondialdehyde (MDA) levels, increases hippocampal SOD activity and glutathione (GSH) levels, and attenuates cognitive impairment in the Morris water maze in a mouse model of D-galactose-induced mild cognitive impairment.4 | [Chemical Properties]
White solid | [Uses]
Pseudoginsenoside F11 is an oxotillol-type ginsenoside which displayes neuroprotective activity. |
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