| Identification | Back Directory | [Name]
1-O-hexadecyl-sn-glycero-2,3-cyclic-phosphate (aMMoniuM salt) | [CAS]
799268-68-1 | [Synonyms]
C16 Cyclic LPA
1-O-hexadecyl-sn-glycero-2,3-cyclic-phosphate (aMMoniuM salt)
1-O-HEXADECYL-SN-GLYCERO-2,3-CYCLIC-PHOSPHATE (AMMONIUM SALT);C16 CYCLIC LPA | [Molecular Formula]
C19H42NO5P | [MDL Number]
MFCD22416843 | [MOL File]
799268-68-1.mol | [Molecular Weight]
395.52 |
| Hazard Information | Back Directory | [Uses]
C16 Cyclic LPA or 1-O-hexadecyl-sn-glycero-2,3-cyclic-phosphate (ammonium salt) has been used as an internal standard for the quantification of lysophosphatidic acid?(LPA) in proton samples using reversed-phase ultra-performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS). | [General Description]
Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). The sn-2 hydroxy group of CPA forms a 5-membered ring with the sn-3 phosphate. | [Biochem/physiol Actions]
cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle, induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells. Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations. |
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