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80-99-9

80-99-9 Structure

80-99-9 Structure
IdentificationBack Directory
[Name]

LATHOSTEROL
[CAS]

80-99-9
[Synonyms]

LATHOSTEROL
γ-Cholestenol
GAMMA-CHOLESTENOL
Cholest-7-en-3-ol
gamma-cholesterol
DELTA7-Cholestenol
7-En-3-cholestanol
5A-cholest-7-en-3B-ol
5α-cholest-7-en-3β-ol
7-Cholesten-3-beta-ol
delta(Sup7)-Cholestenol
(3β,5α)-Cholest-7-en-3-ol
3β-hydroxy-5α,7-cholestene
3β-Hydroxy-5α-cholest-7-ene
Cholest-7-en-3-ol, (3β,5α)-
5ALPHA-CHOLEST-7-EN-3BETA-OL
7,(5-ALPHA)-CHOLESTEN-3-BETA-OL
5Α-CHOLEST-7-EN-3-OL;LATHOSTEROL
3BETA-HYDROXY-5ALPHA,7-CHOLESTENE
(3-beta,5-alpha)-cholest-7-en-3-o
3beta-Hydroxy-5alpha-cholest-7-ene
Cholest-7-en-3-ol, (3beta,5alpha)-
3β-Hydroxy-5α,7-cholestene, Lathosterol
10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
(3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
[Molecular Formula]

C27H46O
[MDL Number]

MFCD00056176
[MOL File]

80-99-9.mol
[Molecular Weight]

386.65
Chemical PropertiesBack Directory
[Melting point ]

126°C
[Boiling point ]

452.8°C (rough estimate)
[density ]

0.9610 (rough estimate)
[refractive index ]

1.5250 (estimate)
[storage temp. ]

-20°C
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
[form ]

Solid
[color ]

White to Off-White
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

FZ7000000
Hazard InformationBack Directory
[Uses]

A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.
[Definition]

ChEBI: A cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3.
[General Description]

Lathosterol is a cholesterol synthesis precursor.
[Biochem/physiol Actions]

5α-Cholest-7-en-3β-ol (Lathosterol) is an intermediate in cholesterol biosynthesis pathway. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol.
[storage]

Store at -20°C
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